HDRC has the following strengths when you consider doing health data research in Asia

Real World Evidence

  • Single payer, consolidated health insurance claims, capturing all reimbursed items.
  • Linkage with Cancer Registry and Mortality.

Rich data in comparison with private health insurance data in North America

  • Low membership turnover rate.
  • Detailed drug use information during hospitalization.
  • Some over-the-counter medication, such as low dose aspirin, are reimbursed and captured in NHI.

Research capability

  • Experienced investigators and analysts who are familiar with the data structure and medical care system in Taiwan
  • Examples of methods being used in recent studies:
    • propensity scores
    • Cox regression with time-dependent covariates
    • nested case-control study
    • self-controlled case series design  
    • case-crossover design
    • interrupted time series analysis
Standard operating procedures and codes have been developed for the operational definitions of exposures, outcomes, and potential confounders.
You may also want to know…
Is there any validation study on NHI claims data?
Yes, there are. Here are some examples (not systematically searched).

1. Cheng, C. L., Kao, Y. H., Lin, S. J., Lee, C. H., & Lai, M. L. (2011). Validation of the National Health Insurance Research Database with ischemic stroke cases in Taiwan. Pharmacoepidemiol Drug Saf, 20(3), 236-242. doi:10.1002/pds.2087

2. Cheng, C. L., Lee, C. H., Chen, P. S., Li, Y. H., Lin, S. J., & Yang, Y. H. (2014). Validation of acute myocardial infarction cases in the national health insurance research database in Taiwan. J Epidemiol, 24(6), 500-507. Retrieved from

3. Sung, S. F., Hsieh, C. Y., Lin, H. J., Chen, Y. W., Yang, Y. H., & Li, C. Y. (2016). Validation of algorithms to identify stroke risk factors in patients with acute ischemic stroke, transient ischemic attack, or intracerebral hemorrhage in an administrative claims database. Int J Cardiol, 215, 277-282. doi:10.1016/j.ijcard.2016.04.069

Can the claims datasets link with electronic medical records?
They are not yet.